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High adiponectin levels linked with decreased diabetes risk
According to the U.S. Centers for disease Control and Prevention, nearly 24 million Americans are living with diabetes, a disease that oftentimes leads the body to become insulin resistant. Out of this 24 million, about 6 million are unaware that they have the disease. Unfortunately, serious complications can happen when diabetes is left untreated, such as amputations, blindness, kidney failure and other serious difficulties.
A study published in the Journal of the American Medical Association may have found a protein created by fat cells, adiponectin, which acts as a hormone with insulin-sensitizing and anti-inflammatory properties. According to the researchers, this finding could eventually lead to helping predict who may develop type 2 diabetes, and may also lead to a pharmacological form of adiponectin.
The study was led by an assistant professor at the Harvard School of Public Health in Boston, Rob M. van Dam. Dam and his colleagues reviewed 13 studies to come to their conclusions that high levels of adiponectin are linked with a decreased risk of diabetes. During their study the average risk reduction was 28 percent per each increase in adiponectin.
Although adiponectin is created by fat cells, adding fat to the diet does not increase the protein – quite the contrary. The more one weighs and the more fat they put on, the less adiponectin is produced. To prevent diabetes it is recommended to lose weight, not gain.
More research is needed to determine whether or not adiponectin can be added to the risk assessment process for diabetes.
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